Receptor Pharmacology in the CNS: Agonists, Antagonists, Inverse Agonists, PAMs, and NAMs

Abstract

A practical conceptual guide to affinity, efficacy, constitutive activity, orthosteric and allosteric binding, and context-dependent CNS signaling. It explains why mechanistic drug labels do not directly predict clinical benefit or safety.

Educational notice: This abstract is for scientific education only. It is not medical advice, diagnosis, or treatment guidance.